23 June 2023 |
Relief Therapeutics is a Swiss, commercial - stage biopharmaceutical company, developing and commercializing novel, patent - protect products in selected specialty, rare and ultra-rare diseases.
We are currently focused on three therapeutic areas where we can best leverage our internal know-how and assets: rare metabolic disorders, rare pulmonary diseases, and rare connective tissue disorders, with particular emphasis on conditions with dermatological manifestations. We also leverage our internal research and development capabilities to identify, develop and commercialize repurposed drugs with proven safety and efficacy.
Our diversified pipeline consists of assets that have the potential to effectively address significant unmet medical needs, including PKU GOLIKE®, engineered with the proprietary Physiomimic™ technology, which is the first prolonged-release amino acid product commercialized for the dietary management of phenylketonuria (PKU). Relief Therapeutics has a collaboration and license agreement with Acer Therapeutics for the worldwide development and commercialization of Olpruva™ (sodium phenylbutyrate) for the treatment of various inborn errors of metabolism, including urea cycle disorders (UCDs) and maple syrup urine disease(MSUD). Relief Therapeutics also continues to develop RLF-100® (aviptadil) for several rare pulmonary indications including pulmonary sarcoidosis, checkpoint inhibitor-induced pneumonitis, non-COVID-19-related acute respiratory distress syndrome, and chronic berylliosis. Relief Therapeutics continues to develop RLF-TD011, a differentiated acid oxidizing solution of hypochlorous acid intended for the treatment of epidermolysis bullosa, an indication for which the U.S. Food and Drug Administration (FDA) has granted Orphan Drug designation. Relief Therapeutics is also exploring the clinical development of RLF-TD011 for the treatment of cutaneous t-cell lymphomas. In addition, Relief Therapeutics is commercializing several legacy products via licensing and distribution partners.
Additional details on our product portfolio can be found on the pipeline page of our website.
Michelle Lock is Relief’s Interim Chief Executive Officer and a member of Relief’s Board of Directors. She has nearly 30 years of biopharmaceutical strategic, operational and commercialization experience.
Paolo Galfetti is Chief Operating Officer. He has over 20 years of management experience in the pharmaceutical sector, including in the areas of business development and licensing, operational strategic management, clinical research, and pharmaceutical discovery and development.
Jeremy Meinen serves as chief financial officer and treasurer. Prior to joining Relief, Jeremy provided financial consulting and controlling services to companies in various industries. Jeremy is a Swiss certified public accountant.
Christopher Wick is Relief Therapeutics’ U.S. Country Lead and is responsible for leading company’s U.S. commercial and sales teams. Prior to joining Relief, Christopher held positions in sales of increasing responsibility at Alexion Pharmaceuticals, Inc., GlaxoSmithKline and Novartis. where he developed and led high-performing, excellence award-winning teams and achieved best-in-the-nation sales for two rare disease products and consistently received top sales rankings.
Michelle Lock is Relief’s Interim Chief Executive Officer and a member of Relief’s Board of Directors. She has nearly 30 years of biopharmaceutical strategic, operational and commercialization experience.
Tom Plitz recently served as Chief Executive Officer of Chord Therapeutics SA, a privately held biopharmaceutical firm based in Geneva, Switzerland, which was acquired by Merck KGaA in January 2022. He has more than two decades of R&D experience from senior management positions in the pharmaceutical industry.
Raghuram (Ram) Selvaraju, Ph.D., MBA, is a Managing Director and Senior Healthcare Analyst in the Equity Research Division of H.C. Wainwright & Co., a New York-based full-service investment bank heavily focused on the healthcare sector. He has over 15 years of experience on Wall Street and previously was a pharmaceutical researcher at Serono in Switzerland. He holds Ph.D. and M.S. degrees from the University of Geneva and an M.B.A. from Cornell University.
Michelle Lock is Relief’s Interim Chief Executive Officer and a member of Relief’s Board of Directors. She has nearly 30 years of biopharmaceutical strategic, operational and commercialization experience.
Patrice Jean is the Chair of the Life Sciences Practice at Hughes Hubbard & Reed, an international law firm based in New York City. She has over a decade of experience counselling leading and startup pharmaceutical, chemical and biotechnology companies in all areas of patent law, including asserting and defending patent rights underlying core technologies and innovations.
Mr. de Svastich is a Managing Director at GEM. Mr. de Svastich has deep expertise in the areas of commercial banking, investment banking and alternative investments.
Their objective was to develop atexakin alfa, a human recombinant version of interleukin-6, for the treatment of peripheral neuropathy.
The Company began rapidly advancing its proprietary asset RLF-100™ into clinical development and towards approval in COVID-19-induced lung injury. In September 2020, Relief entered into a collaboration agreement with NeuroRx, Inc. for the development and commercialization of RLF-100™ (aviptadil).
In March 2021, Relief entered into a collaboration and license agreement with Acer Therapeutics for the worldwide development and commercialization of late-stage development candidate, ACER-001.
In January 2021, Relief signed a binding term sheet to acquire all shares of AdVita. Amongst the AdVita assets being acquired in this transaction, Relief will gain further pending intellectual property rights that may cover RLF-100™ inhaled formulation.
In May 2021, Relief signed a binding term sheet to acquire all outstanding shares of APR Applied Pharma Research. APR already has products on the market in addition to a clinical portfolio in rare or debilitating diseases with high unmet medical need that is synergistic with Relief’s current development pipeline.
In March 2021, Relief’s partner NeuroRx reported top-line 60-day results from the U.S. IV Phase 2b/3 clinical trial evaluating RLF-100™ IV in critical COVID-19 patients with respiratory failure.